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Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade

OBJECTIVE: To test the commonly held assumption that gastric bypass surgery lowers body weight because it limits the ability to eat large amounts of food. DESIGN AND METHODS: Central melanocortin signaling was blocked by ICV infusion of the melanocortin-3/4 receptor antagonist SHU9119 for 14 days in...

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Detalles Bibliográficos
Autores principales: Mumphrey, Michael B., Hao, Zheng, Townsend, R. Leigh, Patterson, Laurel M., Morrison, Christopher D., Münzberg, Heike, Stylopoulos, Nicholas, Ye, Jianping, Berthoud, Hans-Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114988/
https://www.ncbi.nlm.nih.gov/pubmed/24799258
http://dx.doi.org/10.1002/oby.20773