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Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade
OBJECTIVE: To test the commonly held assumption that gastric bypass surgery lowers body weight because it limits the ability to eat large amounts of food. DESIGN AND METHODS: Central melanocortin signaling was blocked by ICV infusion of the melanocortin-3/4 receptor antagonist SHU9119 for 14 days in...
Autores principales: | Mumphrey, Michael B., Hao, Zheng, Townsend, R. Leigh, Patterson, Laurel M., Morrison, Christopher D., Münzberg, Heike, Stylopoulos, Nicholas, Ye, Jianping, Berthoud, Hans-Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114988/ https://www.ncbi.nlm.nih.gov/pubmed/24799258 http://dx.doi.org/10.1002/oby.20773 |
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