Increased blood–brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid

BACKGROUND: Glutaric acid (GA) is a dicarboxylic acid that accumulates in millimolar concentrations in glutaric acidemia I (GA-I), an inherited neurometabolic childhood disease characterized by extensive neurodegeneration. Vascular dysfunction is a common and early pathological feature in GA-I, alth...

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Detalles Bibliográficos
Autores principales: Isasi, Eugenia, Barbeito, Luis, Olivera-Bravo, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115159/
https://www.ncbi.nlm.nih.gov/pubmed/25077029
http://dx.doi.org/10.1186/2045-8118-11-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115159/
https://www.ncbi.nlm.nih.gov/pubmed/25077029
http://dx.doi.org/10.1186/2045-8118-11-15

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