Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

BACKGROUND: Acetylation of lysine residues in histone tails plays an important role in the regulation of gene transcription. Bromdomains are the readers of acetylated histone marks, and, consequently, bromodomain-containing proteins have a variety of chromatin-related functions. Moreover, they are i...

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Detalles Bibliográficos
Autores principales: Philpott, Martin, Rogers, Catherine M, Yapp, Clarence, Wells, Chris, Lambert, Jean-Philippe, Strain-Damerell, Claire, Burgess-Brown, Nicola A, Gingras, Anne-Claude, Knapp, Stefan, Müller, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115480/
https://www.ncbi.nlm.nih.gov/pubmed/25097667
http://dx.doi.org/10.1186/1756-8935-7-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115480/
https://www.ncbi.nlm.nih.gov/pubmed/25097667
http://dx.doi.org/10.1186/1756-8935-7-14

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