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Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders

Disrupted in schizophrenia-1 (DISC1) gene is associated with several neuropsychiatric disorders as it is disrupted by a balanced translocation involving chromosomes 1 and 11 in a large Scottish pedigree with high prevalence of schizophrenia, bipolar disorder and major depression. Since its identific...

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Detalles Bibliográficos
Autores principales: Gómez-Sintes, Raquel, Kvajo, Mirna, Gogos, Joseph A., Lucas, José J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115618/
https://www.ncbi.nlm.nih.gov/pubmed/25126062
http://dx.doi.org/10.3389/fnbeh.2014.00253