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Drofenine: a 2-APB analog with improved selectivity for human TRPV3

Transient receptor potential vanilloid-3 (TRPV3) is a member of the TRPV subfamily of TRP ion channels. The physiological functions of TRPV3 are not fully understood, in part, due to a lack of selective agonists and antagonists that could both facilitate the elucidation of roles for TRPV3 in mammali...

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Detalles Bibliográficos
Autores principales: Deering-Rice, Cassandra E, Mitchell, Virginia K, Romero, Erin G, Abdel Aziz, May H, Ryskamp, Daniel A, Križaj, David, Venkat, Raj Gopal, Reilly, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115637/
https://www.ncbi.nlm.nih.gov/pubmed/25089200
http://dx.doi.org/10.1002/prp2.62