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Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

Cdc42 is a signaling protein important for reorganization of actin cytoskeleton and morphogenesis of cells. However, the functional role of Cdc42 in synaptic plasticity and in behaviors such as learning and memory are not well understood. Here we report that postnatal forebrain deletion of Cdc42 lea...

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Detalles Bibliográficos
Autores principales: Kim, Il Hwan, Wang, Hong, Soderling, Scott H, Yasuda, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115656/
https://www.ncbi.nlm.nih.gov/pubmed/25006034
http://dx.doi.org/10.7554/eLife.02839