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Structural Basis for the Recognition in an Idiotype-Anti-Idiotype Antibody Complex Related to Celiac Disease

Anti-idiotype antibodies have potential therapeutic applications in many fields, including autoimmune diseases. Herein we report the isolation and characterization of AIM2, an anti-idiotype antibody elicited in a mouse model upon expression of the celiac disease-specific autoantibody MB2.8 (directed...

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Detalles Bibliográficos
Autores principales: Vangone, Anna, Abdel-Azeim, Safwat, Caputo, Ivana, Sblattero, Daniele, Di Niro, Roberto, Cavallo, Luigi, Oliva, Romina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116137/
https://www.ncbi.nlm.nih.gov/pubmed/25076134
http://dx.doi.org/10.1371/journal.pone.0102839