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Fibroblast α11β1 Integrin Regulates Tensional Homeostasis in Fibroblast/A549 Carcinoma Heterospheroids

We have previously shown that fibroblast expression of α11β1 integrin stimulates A549 carcinoma cell growth in a xenograft tumor model. To understand the molecular mechanisms whereby a collagen receptor on fibroblast can regulate tumor growth we have used a 3D heterospheroid system composed of A549...

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Detalles Bibliográficos
Autores principales: Lu, Ning, Karlsen, Tine V., Reed, Rolf K., Kusche-Gullberg, Marion, Gullberg, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116160/
https://www.ncbi.nlm.nih.gov/pubmed/25076207
http://dx.doi.org/10.1371/journal.pone.0103173