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Propionibacterium acnes induces IL-1β secretion via the NLRP3 inflammasome in human monocytes

Propionibacterium acnes induction of inflammatory responses is a major etiologic factor contributing to the pathogenesis of acne vulgaris. In particular, the IL-1 family of cytokines plays a critical role in both initiation of acne lesions and in the inflammatory response in acne. In this study, we...

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Detalles Bibliográficos
Autores principales: Qin, Min, Pirouz, Aslan, Kim, Myung-Hwa, Krutzik, Stephan R., Garbán, Hermes J., Kim, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116307/
https://www.ncbi.nlm.nih.gov/pubmed/23884315
http://dx.doi.org/10.1038/jid.2013.309