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Differentiation defects in primary motoneurons from a SMARD1 mouse model that are insensitive to treatment with low dose PEGylated IGF1

Muscle atrophy and diaphragmatic palsy are the clinical characteristics of spinal muscular atrophy with respiratory distress type 1 (SMARD1), and are well represented in the neuromuscular degeneration (Nmd(2J)) mouse, modeling the juvenile form of SMARD1. Both in humans and mice mutations in the IGH...

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Detalles Bibliográficos
Autores principales:	Krieger, Frank, Metzger, Friedrich, Jablonka, Sibylle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116388/ https://www.ncbi.nlm.nih.gov/pubmed/25083343 http://dx.doi.org/10.4161/rdis.29415

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