Diacylglycerol lipase regulates lifespan and oxidative stress response by inversely modulating TOR signaling in Drosophila and C. elegans

Target of rapamycin (TOR) signaling is a nutrient-sensing pathway controlling metabolism and lifespan. Although TOR signaling can be activated by a metabolite of diacylglycerol (DAG), phosphatidic acid (PA), the precise genetic mechanism through which DAG metabolism influences lifespan remains unkno...

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Detalles Bibliográficos
Autores principales: Lin, Yen-Hung, Chen, Yi-Chun, Kao, Tzu-Yu, Lin, Yi-Chun, Hsu, Tzu-En, Wu, Yi-Chun, Ja, William W, Brummel, Theodore J, Kapahi, Pankaj, Yuh, Chiou-Hwa, Yu, Lin-Kwei, Lin, Zhi-Han, You, Ru-Jing, Jhong, Yi-Ting, Wang, Horng-Dar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116436/
https://www.ncbi.nlm.nih.gov/pubmed/24889782
http://dx.doi.org/10.1111/acel.12232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116436/
https://www.ncbi.nlm.nih.gov/pubmed/24889782
http://dx.doi.org/10.1111/acel.12232

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