Cargando…

Diacylglycerol lipase regulates lifespan and oxidative stress response by inversely modulating TOR signaling in Drosophila and C. elegans

Target of rapamycin (TOR) signaling is a nutrient-sensing pathway controlling metabolism and lifespan. Although TOR signaling can be activated by a metabolite of diacylglycerol (DAG), phosphatidic acid (PA), the precise genetic mechanism through which DAG metabolism influences lifespan remains unkno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Yen-Hung, Chen, Yi-Chun, Kao, Tzu-Yu, Lin, Yi-Chun, Hsu, Tzu-En, Wu, Yi-Chun, Ja, William W, Brummel, Theodore J, Kapahi, Pankaj, Yuh, Chiou-Hwa, Yu, Lin-Kwei, Lin, Zhi-Han, You, Ru-Jing, Jhong, Yi-Ting, Wang, Horng-Dar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116436/ https://www.ncbi.nlm.nih.gov/pubmed/24889782 http://dx.doi.org/10.1111/acel.12232

Ejemplares similares

Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27
por: Lien, Wen‐Yu, et al.
Publicado: (2020)

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
por: Li, Lilang, et al.
Publicado: (2022)

One Pot Self-Assembling Fe@PANI Core–Shell Nanowires for Radar Absorption Application
por: Lin, Chung-Kwei, et al.
Publicado: (2023)

Contribution of diacylglycerol lipase β to pain after surgery
por: Luk, Jennifer, et al.
Publicado: (2018)

Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
por: Cavener, Victoria S., et al.
Publicado: (2018)

Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity
por: Yan, Yu-Chuan, et al.
Publicado: (2023)

Rapid antibiotic susceptibility testing of bacteria from patients’ blood via assaying bacterial metabolic response with surface-enhanced Raman spectroscopy
por: Han, Yin-Yi, et al.
Publicado: (2020)

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina
por: Cécyre, Bruno, et al.
Publicado: (2014)

Autophagy-related gene 7 is downstream of heat shock protein 27 in the regulation of eye morphology, polyglutamine toxicity, and lifespan in Drosophila
por: Chen, Shih-Fen, et al.
Publicado: (2012)

Up‐regulation of golgi α‐mannosidase IA and down‐regulation of golgi α‐mannosidase IC activates unfolded protein response during hepatocarcinogenesis
por: Tu, Hsiao‐Chen, et al.
Publicado: (2017)

Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice
por: Chang, Chun-Kai, et al.
Publicado: (2018)

Particulate matters increase epithelial-mesenchymal transition and lung fibrosis through the ETS-1/NF-κB-dependent pathway in lung epithelial cells
por: Chen, Yu-Chen, et al.
Publicado: (2020)

Antitumor and Antimicrobial Activity of Some Cyclic Tetrapeptides and Tripeptides Derived from Marine Bacteria
por: Chakraborty, Subrata, et al.
Publicado: (2015)

FLLL32 Triggers Caspase-Mediated Apoptotic Cell Death in Human Oral Cancer Cells by Regulating the p38 Pathway
por: Su, Chun-Wen, et al.
Publicado: (2021)

A new application of the temporal contiguity effect in designing narrated slideshows
por: Liu, Tzu-Chien, et al.
Publicado: (2022)

Strategies for facilitating processing of transient information in instructional videos by using learner control mechanisms
por: Lin, Yi-Chun, et al.
Publicado: (2022)

Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells
por: Chiou, Guang-Yuh, et al.
Publicado: (2017)

Isocitrate Dehydrogenase Alpha-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans
por: Lin, Zhi-Han, et al.
Publicado: (2022)

Exosomes in clinical trial and their production in compliance with good manufacturing practice
por: Chen, Yu-Shuan, et al.
Publicado: (2019)

Deoxyshikonin Mediates Heme Oxygenase-1 Induction and Apoptotic Response via p38 Signaling in Tongue Cancer Cell Lines
por: Chuang, Chun-Yi, et al.
Publicado: (2022)

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling
por: Keimpema, Erik, et al.
Publicado: (2013)

A novel live cell assay to measure diacylglycerol lipase α activity
por: Singh, Praveen K., et al.
Publicado: (2016)

ABHD11, a new diacylglycerol lipase involved in weight gain regulation
por: Escoubet, Johanna, et al.
Publicado: (2020)

Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa)
por: Schuele, Lena-Louise, et al.
Publicado: (2022)

Vitamin D(3) decreases TNF-α-induced inflammation in lung epithelial cells through a reduction in mitochondrial fission and mitophagy
por: Chen, Yu-Chen, et al.
Publicado: (2021)

Intra-articular injection of N-acetylglucosamine and hyaluronic acid combined with PLGA scaffolds for osteochondral repair in rabbits
por: Wang, Hsueh-Chun, et al.
Publicado: (2018)

Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii
por: Rostami-Mansoor, Sahar, et al.
Publicado: (2021)

Electric Stimulation of Ear Reduces the Effect of Toll-Like Receptor 4 Signaling Pathway on Kainic Acid-Induced Epileptic Seizures in Rats
por: Liao, En-Tzu, et al.
Publicado: (2018)

Overexpression of Endothelin 1 Triggers Hepatocarcinogenesis in Zebrafish and Promotes Cell Proliferation and Migration through the AKT Pathway
por: Lu, Jeng-Wei, et al.
Publicado: (2014)

HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans
por: Chen, Di, et al.
Publicado: (2009)

Perilla frutescens Leaf Extract Inhibits Mite Major Allergen Der p 2-induced Gene Expression of Pro-Allergic and Pro-Inflammatory Cytokines in Human Bronchial Epithelial Cell BEAS-2B
por: Liu, Jer-Yuh, et al.
Publicado: (2013)

CaMKII is a novel regulator of diacylglycerol lipase-α and striatal endocannabinoid signaling
por: Shonesy, Brian C., et al.
Publicado: (2013)

Effects of Starvation on the Levels of Triglycerides, Diacylglycerol, and Activity of Lipase in Male and Female Drosophila Melanogaster
por: Chauhan, Ved, et al.
Publicado: (2021)

Salvage surgeries for splanchnic artery aneurysms after failed endovascular therapy: case series
por: Lin, Yi-Chun, et al.
Publicado: (2023)

Association between diacylglycerol kinase kappa variants and hypospadias susceptibility in a Han Chinese population
por: Xie, Hua, et al.
Publicado: (2018)

Magnolol Triggers Caspase-Mediated Apoptotic Cell Death in Human Oral Cancer Cells through JNK1/2 and p38 Pathways
por: Chen, Yi-Tzu, et al.
Publicado: (2021)

STIM1 Knockout Enhances PDGF-Mediated Ca(2+) Signaling through Upregulation of the PDGFR–PLCγ–STIM2 Cascade
por: Huang, Tzu-Yu, et al.
Publicado: (2018)

AI-Assisted Fusion of Scanning Electrochemical Microscopy Images Using Novel Soft Probe
por: Lin, Yi-Hong, et al.
Publicado: (2022)

Developing a Robotic Surgical Platform Is Beneficial to the Implementation of the ERAS Program for Colorectal Surgery: An Outcome and Learning Curve Analysis
por: Hung, Chun-Yen, et al.
Publicado: (2023)

Myeloid-Specific Deletion of Diacylglycerol Lipase α Inhibits Atherogenesis in ApoE-Deficient Mice
por: Jehle, Julian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k86d36gqtuk4s9evgva380ushs