Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

Attenuated growth hormone and insulin-like growth factor-1 (GH/IGF-1) signaling is associated with extended lifespan in several animal models. However, the effect of diminished GH/IGF-1 activity on survival in humans has not been confirmed. We tested the hypothesis that IGF-1 levels in nonagenarians...

Descripción completa

Detalles Bibliográficos
Autores principales: Milman, Sofiya, Atzmon, Gil, Huffman, Derek M, Wan, Junxiang, Crandall, Jill P, Cohen, Pinchas, Barzilai, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116456/
https://www.ncbi.nlm.nih.gov/pubmed/24618355
http://dx.doi.org/10.1111/acel.12213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116456/
https://www.ncbi.nlm.nih.gov/pubmed/24618355
http://dx.doi.org/10.1111/acel.12213

Ejemplares similares