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Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells

Tobacco smoke (TS) is a major cause of human bladder cancer (BC). Two components in TS, 4-aminobiphenyl (4-ABP) and acrolein, which also are environmental contaminants, can cause bladder tumor in rat models. Their role in TS related BC has not been forthcoming. To establish the relationship between...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-Wook, Wang, Hsiang-Tsui, Weng, Mao-wen, Hu, Yu, Chen, Wei-sheng, Chou, David, Liu, Yan, Donin, Nicholas, Huang, William C., Lepor, Herbert, Wu, Xue-Ru, Wang, Hailin, Beland, Frederick A., Tang, Moon-shong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116500/
https://www.ncbi.nlm.nih.gov/pubmed/24939871