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The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy

Docosahexaenoic acid (DHA), an omega-3 C22 natural fatty acid serving as a precursor for metabolic and biochemical pathways, was reported as a targeting ligand of anticancer drugs. However, its tumor targeting ability and mechanism has not been claimed. Here we hypothesized that the uptake of DHA by...

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Detalles Bibliográficos
Autores principales: Li, Siwen, Qin, Jingyi, Tian, Caiping, Cao, Jie, Fida, Guissi, Wang, Zhaohui, Chen, Haiyan, Qian, Zhiyu, Chen, Wei R, Gu, Yueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116508/
https://www.ncbi.nlm.nih.gov/pubmed/25004114