Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma

Tumor control of hepatocellular carcinoma by radiotherapy remains unsatisfactory. The phosphatidylinositol 3-kinase (PI3K)/Akt pathway plays a critical role in inhibiting cancer cell death. Elevated PI3K/Akt activity is associated with increased cellular resistance to irradiation. Our aim was to det...

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Detalles Bibliográficos
Autores principales: Liu, Wei-Lin, Gao, Ming, Tzen, Kai-Yuan, Tsai, Chiao-Ling, Hsu, Feng-Ming, Cheng, Ann-Lii, Cheng, Jason Chia-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116511/
https://www.ncbi.nlm.nih.gov/pubmed/25004403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116511/
https://www.ncbi.nlm.nih.gov/pubmed/25004403

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