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Brachyury regulates proliferation of cancer cells via a p27(Kip1-)dependent pathway

The T-box transcription factor Brachyury is expressed in a number of tumour types and has been demonstrated to have cancer inducing properties. To date, it has been linked to cancer associated induction of epithelial to mesenchymal transition, tumour metastasis and expression of markers for cancer s...

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Detalles Bibliográficos
Autores principales: Jezkova, Jana, Williams, Jason S., Jones-Hutchins, Ffion, Sammut, Stephen J., Gollins, Simon, Cree, Ian, Coupland, Sarah, McFarlane, Ramsay J., Wakeman, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116522/
https://www.ncbi.nlm.nih.gov/pubmed/25003467