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Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus

Although apoptotic phenomena have been observed in malignant cells infected by measles virus vaccine strain Edmonston B (MV-Edm), the precise oncolytic mechanisms are poorly defined. In this study we found that MV-Edm induced autophagy and sequestosome 1-mediated mitophagy leading to decreased cytoc...

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Detalles Bibliográficos
Autores principales: Xia, Mao, Meng, Gang, Jiang, Aiqin, Chen, Aiping, Dahlhaus, Meike, Gonzalez, Patrick, Beltinger, Christian, Wei, Jiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116530/
https://www.ncbi.nlm.nih.gov/pubmed/25004098