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Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus
Although apoptotic phenomena have been observed in malignant cells infected by measles virus vaccine strain Edmonston B (MV-Edm), the precise oncolytic mechanisms are poorly defined. In this study we found that MV-Edm induced autophagy and sequestosome 1-mediated mitophagy leading to decreased cytoc...
Autores principales: | Xia, Mao, Meng, Gang, Jiang, Aiqin, Chen, Aiping, Dahlhaus, Meike, Gonzalez, Patrick, Beltinger, Christian, Wei, Jiwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116530/ https://www.ncbi.nlm.nih.gov/pubmed/25004098 |
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