Recombinant viral capsid protein VP1 suppresses lung cancer metastasis by inhibiting COX-2/PGE2 and MIG-7

Recombinant capsid protein VP1 (rVP1) of foot-and-mouth disease virus binds to integrins to modulate Akt/GSK3-β signaling and suppress migration/invasion and metastasis of cancer cells, but the underlying molecular mechanism is unclear. Here, we showed that the rVP1-mediated inhibition of Akt/GSK3-β...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Ming-Yi, Hung, Shao-Wen, Liang, Chi-Ming, Liang, Shu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116532/
https://www.ncbi.nlm.nih.gov/pubmed/25004182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116532/
https://www.ncbi.nlm.nih.gov/pubmed/25004182

Ejemplares similares