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Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress

Males develop kidney stones far more frequently than females with a ratio of 2–3:1, suggesting that androgen receptor (AR) signaling might play a key role in the development of nephrolithiasis. Using the cre-loxP system to selectively knock out AR in glyoxylate-induced calcium oxalate (CaOx) crystal...

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Detalles Bibliográficos
Autores principales: Liang, Liang, Li, Lei, Tian, Jing, Lee, Soo Ok, Dang, Qiang, Huang, Chiung-Kuei, Yeh, Shuyuan, Erturk, Erdal, Bushinsky, David, Chang, Luke S., He, Dalin, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116591/
https://www.ncbi.nlm.nih.gov/pubmed/24956378
http://dx.doi.org/10.1210/me.2014-1047