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Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress
Males develop kidney stones far more frequently than females with a ratio of 2–3:1, suggesting that androgen receptor (AR) signaling might play a key role in the development of nephrolithiasis. Using the cre-loxP system to selectively knock out AR in glyoxylate-induced calcium oxalate (CaOx) crystal...
Autores principales: | Liang, Liang, Li, Lei, Tian, Jing, Lee, Soo Ok, Dang, Qiang, Huang, Chiung-Kuei, Yeh, Shuyuan, Erturk, Erdal, Bushinsky, David, Chang, Luke S., He, Dalin, Chang, Chawnshang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116591/ https://www.ncbi.nlm.nih.gov/pubmed/24956378 http://dx.doi.org/10.1210/me.2014-1047 |
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