Carbohydrate-Based Ice Recrystallization Inhibitors Increase Infectivity and Thermostability of Viral Vectors

The inability of vaccines to retain sufficient thermostability has been an obstacle to global vaccination programs. To address this major limitation, we utilized carbohydrate-based ice recrystallization inhibitors (IRIs) to eliminate the cold chain and stabilize the potency of Vaccinia virus (VV), V...

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Detalles Bibliográficos
Autores principales: Ghobadloo, Shahrokh M., Balcerzak, Anna K., Gargaun, Ana, Muharemagic, Darija, Mironov, Gleb G., Capicciotti, Chantelle J., Briard, Jennie G., Ben, Robert N., Berezovski, Maxim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116624/
https://www.ncbi.nlm.nih.gov/pubmed/25078058
http://dx.doi.org/10.1038/srep05903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116624/
https://www.ncbi.nlm.nih.gov/pubmed/25078058
http://dx.doi.org/10.1038/srep05903

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