Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma

Asthma is characterized by airway inflammation. Inflammation is associated with oxidant stress. Airway epithelial cells are shielded from this stress by a thin layer of lung lining fluid (LLF) which contains an abundance of the antioxidant glutathione. LLF glutathione metabolism is regulated by γ-gl...

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Detalles Bibliográficos
Autores principales: Tuzova, Marina, Jean, Jyh-Chang, Hughey, Rebecca P., Brown, Lou Ann S., Cruikshank, William W., Hiratake, Jun, Joyce-Brady, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116799/
https://www.ncbi.nlm.nih.gov/pubmed/25132819
http://dx.doi.org/10.3389/fphar.2014.00179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116799/
https://www.ncbi.nlm.nih.gov/pubmed/25132819
http://dx.doi.org/10.3389/fphar.2014.00179

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