ALS associated mutant SOD1 impairs the motor neurons and astrocytes and wild type astrocyte secreted-factors reverse the impaired motor neurons

BACKGROUND: Amyotrophic Lateral Sclerosis, in which motor neurons degenerate, leading to paralysis, not only the affected motor neurons, but the surrounding non-neuronal cells also contribute significantly to the disease. However, the disease mechanism is not known. PURPOSE: In this study we have ad...

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Detalles Bibliográficos
Autores principales: Thangavelu, Soundara Rajan, Tripathi, Prem Prakash, Arya, Upasna, Mishra, Himanshu K., Subramaniam, Jamuna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117032/
https://www.ncbi.nlm.nih.gov/pubmed/25205921
http://dx.doi.org/10.5214/ans.0972.7531.1118205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117032/
https://www.ncbi.nlm.nih.gov/pubmed/25205921
http://dx.doi.org/10.5214/ans.0972.7531.1118205

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