Gene-based therapy of Parkinson’s Disease: Translation from animal model to human clinical trial employing convection enhanced delivery

The existing treatment of Parkinson’s disease (PD) is directed towards substituting dopamine loss with either dopamine replacement therapy or pharmacological therapies aimed at increasing dopamine at the synapse level. Emerging viable alternatives include the use of cell-based and gene-based therape...

Descripción completa

Detalles Bibliográficos
Autores principales: Miranpuri, Gurwattan S., Kumbier, Lauren, Hinchman, Angelica, Schomberg, Dominic, Wang, Anyi, Marshall, Hope, Kubota, Ken, Ross, Chris, Sillay, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2012
Materias:
Comprehensive Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117084/
https://www.ncbi.nlm.nih.gov/pubmed/25205986
http://dx.doi.org/10.5214/ans.0972.7531.190310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117084/
https://www.ncbi.nlm.nih.gov/pubmed/25205986
http://dx.doi.org/10.5214/ans.0972.7531.190310

Ejemplares similares