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Convection enhanced delivery to the Brain: preparing for gene therapy and protein delivery to the Brain for functional and restorative Neurosurgery by understanding low-flow neurocatheter infusions using the Alaris(®) system infusion pump

BACKGROUND: Convection enhanced delivery (CED) is an emerging form of direct brain infusion therapy employed in human functional and restorative neurosurgery clinical trials delivering protein, viral vectors for gene therapy, and siRNA. PURPOSE: Pressure monitoring has become a vital tool in ensurin...

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Detalles Bibliográficos
Autores principales: Sillay, Karl, Hinchman, Angelica, Akture, Erinc, Salamat, Shahriar, Miranpuri, Gurwattan, Williams, Justin, Berndt, Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117106/
https://www.ncbi.nlm.nih.gov/pubmed/25206013
http://dx.doi.org/10.5214/ans.0972.7531.200205