Concerning RNA-guided gene drives for the alteration of wild populations

Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a genera...

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Detalles Bibliográficos
Autores principales: Esvelt, Kevin M, Smidler, Andrea L, Catteruccia, Flaminia, Church, George M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Ecology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117217/
https://www.ncbi.nlm.nih.gov/pubmed/25035423
http://dx.doi.org/10.7554/eLife.03401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117217/
https://www.ncbi.nlm.nih.gov/pubmed/25035423
http://dx.doi.org/10.7554/eLife.03401

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