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Apoptotic Lymphocytes of H. sapiens Lose Nucleosomes in GC-Rich Promoters

We analyzed two sets of human CD4(+) nucleosomal DNA directly sequenced by Illumina (Solexa) high throughput sequencing method. The first set has ∼40 M sequences and was produced from the normal CD4+ T lymphocytes by micrococcal nuclease. The second set has ∼44 M sequences and was obtained from peri...

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Detalles Bibliográficos
Autores principales: Hosid, Sergey, Ioshikhes, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117428/
https://www.ncbi.nlm.nih.gov/pubmed/25077608
http://dx.doi.org/10.1371/journal.pcbi.1003760