Robustness and Evolvability of the Human Signaling Network

Biological systems are known to be both robust and evolvable to internal and external perturbations, but what causes these apparently contradictory properties? We used Boolean network modeling and attractor landscape analysis to investigate the evolvability and robustness of the human signaling netw...

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Detalles Bibliográficos
Autores principales: Kim, Junil, Vandamme, Drieke, Kim, Jeong-Rae, Munoz, Amaya Garcia, Kolch, Walter, Cho, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117429/
https://www.ncbi.nlm.nih.gov/pubmed/25077791
http://dx.doi.org/10.1371/journal.pcbi.1003763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117429/
https://www.ncbi.nlm.nih.gov/pubmed/25077791
http://dx.doi.org/10.1371/journal.pcbi.1003763

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