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Regulation of Feto-Maternal Barrier by Matriptase- and PAR-2-Mediated Signaling Is Required for Placental Morphogenesis and Mouse Embryonic Survival
The development of eutherian mammalian embryos is critically dependent on the selective bi-directional transport of molecules across the placenta. Here, we uncover two independent and partially redundant protease signaling pathways that include the membrane-anchored serine proteases, matriptase and...
Autores principales: | Szabo, Roman, Peters, Diane E., Kosa, Peter, Camerer, Eric, Bugge, Thomas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117450/ https://www.ncbi.nlm.nih.gov/pubmed/25078604 http://dx.doi.org/10.1371/journal.pgen.1004470 |
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