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Redox State and Mitochondrial Respiratory Chain Function in Skeletal Muscle of LGMD2A Patients

BACKGROUND: Calpain-3 deficiency causes oxidative and nitrosative stress-induced damage in skeletal muscle of LGMD2A patients, but mitochondrial respiratory chain function and anti-oxidant levels have not been systematically assessed in this clinical population previously. METHODS: We identified 14...

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Detalles Bibliográficos
Autores principales: Nilsson, Mats I., Macneil, Lauren G., Kitaoka, Yu, Alqarni, Fatimah, Suri, Rahul, Akhtar, Mahmood, Haikalis, Maria E., Dhaliwal, Pavneet, Saeed, Munim, Tarnopolsky, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117472/
https://www.ncbi.nlm.nih.gov/pubmed/25079074
http://dx.doi.org/10.1371/journal.pone.0102549