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Intraganglionic Signaling as a Novel Nasal-Meningeal Pathway for TRPA1-Dependent Trigeminovascular Activation by Inhaled Environmental Irritants

Headache is the most common symptom associated with air pollution, but little is understood about the underlying mechanism. Nasal administration of environmental irritants activates the trigeminovascular system by a TRPA1-dependent process. This report addresses questions about the anatomical pathwa...

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Detalles Bibliográficos
Autores principales: Kunkler, Phillip Edward, Ballard, Carrie Jo, Pellman, Jessica Joan, Zhang, LuJuan, Oxford, Gerry Stephen, Hurley, Joyce Harts
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117521/
https://www.ncbi.nlm.nih.gov/pubmed/25077949
http://dx.doi.org/10.1371/journal.pone.0103086