Cargando…
Intraganglionic Signaling as a Novel Nasal-Meningeal Pathway for TRPA1-Dependent Trigeminovascular Activation by Inhaled Environmental Irritants
Headache is the most common symptom associated with air pollution, but little is understood about the underlying mechanism. Nasal administration of environmental irritants activates the trigeminovascular system by a TRPA1-dependent process. This report addresses questions about the anatomical pathwa...
Autores principales: | Kunkler, Phillip Edward, Ballard, Carrie Jo, Pellman, Jessica Joan, Zhang, LuJuan, Oxford, Gerry Stephen, Hurley, Joyce Harts |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117521/ https://www.ncbi.nlm.nih.gov/pubmed/25077949 http://dx.doi.org/10.1371/journal.pone.0103086 |
Ejemplares similares
-
Role of intraganglionic transmission in the trigeminovascular pathway
por: Zhang, LuJuan, et al.
Publicado: (2019) -
Intraganglionic reactive oxygen species mediate inflammatory pain and hyperalgesia through TRPA1 in the rat
por: Zhang, Youping, et al.
Publicado: (2023) -
Environmental toxin acrolein alters levels of endogenous lipids, including TRP agonists: A potential mechanism for headache driven by TRPA1 activation
por: Leishman, Emma, et al.
Publicado: (2017) -
Nasal TRPA1 mediates irritant‐induced bradypnea in mice
por: Inui, Keiichi, et al.
Publicado: (2016) -
TRPA1-Mediated Src Family Kinases Activity Facilitates Cortical Spreading Depression Susceptibility and Trigeminovascular System Sensitization
por: Nie, Lingdi, et al.
Publicado: (2021)