Proteasome Inhibitors Alter Levels of Intracellular Peptides in HEK293T and SH-SY5Y Cells

The proteasome cleaves intracellular proteins into peptides. Earlier studies found that treatment of human embryonic kidney 293T (HEK293T) cells with epoxomicin (an irreversible proteasome inhibitor) generally caused a decrease in levels of intracellular peptides. However, bortezomib (an antitumor d...

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Detalles Bibliográficos
Autores principales: Dasgupta, Sayani, Castro, Leandro M., Dulman, Russell, Yang, Ciyu, Schmidt, Marion, Ferro, Emer S., Fricker, Lloyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117522/
https://www.ncbi.nlm.nih.gov/pubmed/25079948
http://dx.doi.org/10.1371/journal.pone.0103604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117522/
https://www.ncbi.nlm.nih.gov/pubmed/25079948
http://dx.doi.org/10.1371/journal.pone.0103604

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