Cargando…

Polarized Axonal Surface Expression of Neuronal KCNQ Potassium Channels Is Regulated by Calmodulin Interaction with KCNQ2 Subunit

KCNQ potassium channels composed of KCNQ2 and KCNQ3 subunits give rise to the M-current, a slow-activating and non-inactivating voltage-dependent potassium current that limits repetitive firing of action potentials. KCNQ channels are enriched at the surface of axons and axonal initial segments, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Cavaretta, John P., Sherer, Kaitlyn R., Lee, Kwan Young, Kim, Edward H., Issema, Rodal S., Chung, Hee Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117524/
https://www.ncbi.nlm.nih.gov/pubmed/25077630
http://dx.doi.org/10.1371/journal.pone.0103655