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Activating Transcription Factor 4 Promotes Esophageal Squamous Cell Carcinoma Invasion and Metastasis in Mice and Is Associated with Poor Prognosis in Human Patients

BACKGROUND: Activating transcription factor 4 (ATF4) is a stress response gene that is involved in homeostasis and cellular protection. However, its expression and function in esophageal squamous cell carcinoma (ESCC) remains unknown. In this study, we aimed to determine the clinicopathologic signif...

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Detalles Bibliográficos
Autores principales: Zhu, Hongwu, Chen, Xiong, Chen, Bin, Chen, Bei, Song, Weibing, Sun, Dayong, Zhao, Yagang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117569/
https://www.ncbi.nlm.nih.gov/pubmed/25078779
http://dx.doi.org/10.1371/journal.pone.0103882