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Inhibition of Euchromatic Histone Methyltransferase 1 and 2 Sensitizes Chronic Myeloid Leukemia Cells to Interferon Treatment

BACKGROUND: H3K9 methylation is one of the essential histone post-translational modifications for heterochromatin formation and transcriptional repression. Recently, several studies have demonstrated that H3K9 methylation negatively regulates the type I interferon response. RESULTS: We report the ap...

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Detalles Bibliográficos
Autores principales: Loh, Sheng Wei, Ng, Wei Lun, Yeo, Kok Siong, Lim, Yat-Yuen, Ea, Chee-Kwee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117596/
https://www.ncbi.nlm.nih.gov/pubmed/25079219
http://dx.doi.org/10.1371/journal.pone.0103915