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Non-Coding Polymorphisms in Nucleotide Binding Domain 1 in ABCC1 Gene Associate with Transcript Level and Survival of Patients with Breast Cancer

OBJECTIVES: ATP-Binding Cassette (ABC) transporters may cause treatment failure by transporting of anticancer drugs outside of the tumor cells. Multidrug resistance-associated protein 1 coded by the ABCC1 gene has recently been suggested as a potential prognostic marker in breast cancer patients. Th...

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Detalles Bibliográficos
Autores principales: Kunická, Tereza, Václavíková, Radka, Hlaváč, Viktor, Vrána, David, Pecha, Václav, Rauš, Karel, Trnková, Markéta, Kubáčková, Kateřina, Ambruš, Miloslav, Vodičková, Ludmila, Vodička, Pavel, Souček, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117604/
https://www.ncbi.nlm.nih.gov/pubmed/25078270
http://dx.doi.org/10.1371/journal.pone.0101740