A Molecularly Cloned, Live-Attenuated Japanese Encephalitis Vaccine SA(14)-14-2 Virus: A Conserved Single Amino Acid in the ij Hairpin of the Viral E Glycoprotein Determines Neurovirulence in Mice

Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that causes fatal neurological disease in humans, is one of the most important emerging pathogens of public health significance. JEV represents the JE serogroup, which also includes West Nile, Murray Valley encephalitis, and St. Louis en...

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Detalles Bibliográficos
Autores principales: Yun, Sang-Im, Song, Byung-Hak, Kim, Jin-Kyoung, Yun, Gil-Nam, Lee, Eun-Young, Li, Long, Kuhn, Richard J., Rossmann, Michael G., Morrey, John D., Lee, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117607/
https://www.ncbi.nlm.nih.gov/pubmed/25077483
http://dx.doi.org/10.1371/journal.ppat.1004290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117607/
https://www.ncbi.nlm.nih.gov/pubmed/25077483
http://dx.doi.org/10.1371/journal.ppat.1004290

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