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Spatial confinement is a major determinant of the folding landscape of human chromosomes

The global architecture of the cell nucleus and the spatial organization of chromatin play important roles in gene expression and nuclear function. Single-cell imaging and chromosome conformation capture-based techniques provide a wealth of information on the spatial organization of chromosomes. How...

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Detalles Bibliográficos
Autores principales: Gürsoy, Gamze, Xu, Yun, Kenter, Amy L., Liang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117743/
https://www.ncbi.nlm.nih.gov/pubmed/24990374
http://dx.doi.org/10.1093/nar/gku462