Cargando…
Spatial confinement is a major determinant of the folding landscape of human chromosomes
The global architecture of the cell nucleus and the spatial organization of chromatin play important roles in gene expression and nuclear function. Single-cell imaging and chromosome conformation capture-based techniques provide a wealth of information on the spatial organization of chromosomes. How...
Autores principales: | Gürsoy, Gamze, Xu, Yun, Kenter, Amy L., Liang, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117743/ https://www.ncbi.nlm.nih.gov/pubmed/24990374 http://dx.doi.org/10.1093/nar/gku462 |
Ejemplares similares
-
Computational construction of 3D chromatin ensembles and prediction of functional interactions of alpha-globin locus from 5C data
por: Gürsoy, Gamze, et al.
Publicado: (2017) -
Spatial organization of the budding yeast genome in the cell nucleus and identification of specific chromatin interactions from multi-chromosome constrained chromatin model
por: Gürsoy, Gamze, et al.
Publicado: (2017) -
Simulated binding of transcription factors to active and inactive regions folds human chromosomes into loops, rosettes and topological domains
por: Brackley, Chris A., et al.
Publicado: (2016) -
Anomalous diffusion, spatial coherence, and viscoelasticity from the energy landscape of human chromosomes
por: Di Pierro, Michele, et al.
Publicado: (2018) -
The landscape of human SVA retrotransposons
por: Chu, Chong, et al.
Publicado: (2023)