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Ultrasensitive isolation, identification and quantification of DNA–protein adducts by ELISA-based RADAR assay

Enzymes that form transient DNA–protein covalent complexes are targets for several potent classes of drugs used to treat infectious disease and cancer, making it important to establish robust and rapid procedures for analysis of these complexes. We report a method for isolation of DNA–protein adduct...

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Detalles Bibliográficos
Autores principales: Kiianitsa, Kostantin, Maizels, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117749/
https://www.ncbi.nlm.nih.gov/pubmed/24914050
http://dx.doi.org/10.1093/nar/gku490