Uncoupling of the dynamics of host–pathogen interaction uncovers new mechanisms of viral interferon antagonism at the single-cell level

Antiviral defence in mammals is mediated through type-I interferons (IFNs). Viruses antagonise this process through expression of IFN antagonist proteins (IAPs). Understanding and modelling of viral escape mechanisms and the dynamics of IAP action has the potential to facilitate the development of s...

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Detalles Bibliográficos
Autores principales: Rand, Ulfert, Hillebrand, Upneet, Sievers, Stephanie, Willenberg, Steffi, Köster, Mario, Hauser, Hansjörg, Wirth, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117750/
https://www.ncbi.nlm.nih.gov/pubmed/24895433
http://dx.doi.org/10.1093/nar/gku492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117750/
https://www.ncbi.nlm.nih.gov/pubmed/24895433
http://dx.doi.org/10.1093/nar/gku492

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