Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation

DNA methylation is a central epigenetic modification in mammals, with essential roles in development and disease. De novo DNA methyltransferases establish DNA methylation patterns in specific regions within the genome by mechanisms that remain poorly understood. Here we show that protein citrullinat...

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Detalles Bibliográficos
Autores principales: Deplus, Rachel, Denis, Hélène, Putmans, Pascale, Calonne, Emilie, Fourrez, Marie, Yamamoto, Kazuhiko, Suzuki, Akari, Fuks, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117755/
https://www.ncbi.nlm.nih.gov/pubmed/24957603
http://dx.doi.org/10.1093/nar/gku522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117755/
https://www.ncbi.nlm.nih.gov/pubmed/24957603
http://dx.doi.org/10.1093/nar/gku522

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