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Two cationic porphyrin isomers showing different multimeric G-quadruplex recognition specificity against monomeric G-quadruplexes

Ligands that can interact specifically with telomeric multimeric G-quadruplexes could be developed as promising anticancer drugs with few side effects related to other G-quadruplex-forming regions. In this paper, a new cationic porphyrin derivative, m-TMPipEOPP, was synthesized and characterized. It...

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Detalles Bibliográficos
Autores principales: Huang, Xiao-Xi, Zhu, Li-Na, Wu, Bin, Huo, Yan-Fang, Duan, Na-Na, Kong, De-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117758/
https://www.ncbi.nlm.nih.gov/pubmed/24939896
http://dx.doi.org/10.1093/nar/gku526