A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator

Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that modifies histone tails. To help elucidate the biological function of PRMT6 in vivo, we generated transgenic mice that ubiquitously express PRMT6 fused to the hormone-binding portion of the estrogen receptor (ER*). The ER*-PRMT6 fu...

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Detalles Bibliográficos
Autores principales: Di Lorenzo, Alessandra, Yang, Yanzhong, Macaluso, Marc, Bedford, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117762/
https://www.ncbi.nlm.nih.gov/pubmed/24939901
http://dx.doi.org/10.1093/nar/gku530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117762/
https://www.ncbi.nlm.nih.gov/pubmed/24939901
http://dx.doi.org/10.1093/nar/gku530

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