Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends

Telomerase, a ribonucleoprotein complex, is responsible for maintaining the telomere length at chromosome ends. Using its RNA component as a template, telomerase uses its reverse transcriptase activity to extend the 3′-end single-stranded, repetitive telomeric DNA sequence. Pif1, a 5′-to-3′ helicase...

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Detalles Bibliográficos
Autores principales: Li, Jing-Ru, Yu, Tai-Yuan, Chien, I-Chieh, Lu, Chia-Ying, Lin, Jing-Jer, Li, Hung-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117769/
https://www.ncbi.nlm.nih.gov/pubmed/24981509
http://dx.doi.org/10.1093/nar/gku541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117769/
https://www.ncbi.nlm.nih.gov/pubmed/24981509
http://dx.doi.org/10.1093/nar/gku541

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