SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner

Androgen receptor (AR) plays an important regulatory role in prostate cancer. AR's transcriptional activity is regulated by androgenic ligands, but also by post-translational modifications, such as SUMOylation. To study the role of AR SUMOylation in genuine chromatin environment, we compared an...

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Detalles Bibliográficos
Autores principales: Sutinen, Päivi, Malinen, Marjo, Heikkinen, Sami, Palvimo, Jorma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117771/
https://www.ncbi.nlm.nih.gov/pubmed/24981513
http://dx.doi.org/10.1093/nar/gku543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117771/
https://www.ncbi.nlm.nih.gov/pubmed/24981513
http://dx.doi.org/10.1093/nar/gku543

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